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Best Describes the Mode of Action of Aminoglycoside

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Aminoglycosides macrolides lincosamides streptogramins chloramphenicol tetracyclines. They inhibit protein synthesis Can both Gram-positive and gram-negative bacteria use the same mechanism of resistance to an. Pin On Grad School Penicillin shows a synergistic effect with aminoglycosides since the inhibition of peptidoglycan synthesis allows aminoglycosides to penetrate the bacterial cell wall more easily allowing their disruption of bacterial protein synthesis within the cell. . They inhibit cell wall synthesis. Post antibiotic effect Aminoglycosides exhibit concentration dependent killing. This results in a lowered MBC for susceptible organisms. This review describes the current understanding of streptogramin function and resistance with emphasis on molecular mechanism and epidemiology. 1 Antimicrobial Mechanism of Action Aminoglycosides are amongst the most important compounds used to treat serious nosocomial infections...